NOT KNOWN FACTUAL STATEMENTS ABOUT ABBV-744

Proteolysis-concentrating on chimeras (PROTACs) and molecular glue degraders (MGDs) are the most maturely developed TPD strategies. On this overview, we center on both preclinical experiments and scientific trials to deliver an extensive summary of the safety and clinical success of PROTACs and MGDs in hematologic malignancies in the last 20 years.